The Southwest Region covers the area along the Victoria Highway from the Buntine Highway, 125 km west of Katherine, to Keep River National Park, on the Western Australian border.

A little over 230 species, including White-quilled Rock-Pigeon and Purple-crowned Fairy-wren, have been recorded in the region. The region is renowned for its finches, with eleven species recorded. In addition to this, there are many other birds here that are either absent or rare elsewhere in the Top End. These include Spinifex Pigeon, Grey-fronted Honeyeater, Red-capped Robin, Crimson Chat and Pictorella Mannikin. The Victoria Highway can be a haven for raptors. Grey Falcon, Square-tailed Kite, Black-breasted Buzzard and Spotted Harrier are reported more regularly from here than elsewhere in the Top End.

In addition to the specific sites described here, stop at creek crossings, particularly when water levels are low, as birds come to drink at the remnant pools at all times of day. Stopping to look in areas where incidental bird activity is observed can also result in finding some of the nomadic birds that are normally difficult to locate.

There are camping facilities at Victoria River, Timber Creek and within Gregory and Keep River National Parks. There are hotel and fuel facilities in Timber Creek and Victoria River.